Estimating Risk from Small Inocula by Using Population Growth Parameters

Estimating risk from small inocula by using population growth parameters.

Risk from an uncertain small inoculum depends on variability of single-cell lag times. However, quantifying single-cell variability is technically challenging. It is possible to estimate this variability using population growth parameters. We demonstrate this possibility using data from literature and show a Bayesian scheme for performing this task.

Estimating ancestral population parameters.

The expected numbers of different categories of polymorphic sites are derived for two related models of population history the isolation model, in which an ancestral population splits into two descendents, and the size-change model, in which a single population undergoes an instantaneous change in size. For the isolation model, the observed numbers of shared, fixed, and exclusive polymorphic si...

Estimating Risk Parameters

estimating claims reserves using ibnr reserves

شرکت های بیمه در قبال بیمه گذاران متعهد می شوند که به ازای دریافت حق بیمه، خسارت وارده به بیمه گذاران را جبران نمایند. بنابراین بیمه گر همیشه مبالغی را بر عهده دارد که متعلق به بیمه گذاران است و مربوط به تعهدات آینده می باشد. این مبالغ را ذخایر فنی یا technical reserves گویند. بیمه گر موظف است در پایان سال مالی، هنگام بستن حساب ها، ذخایر فنی را محاسبه و نگهداری کند. پس از وقوع خسارت، بیمه گذار ...

Growth-enhancing factor for human tubercle bacilli using minute inocula.

It has been difficult to cultivate human tubercle bacilli in agar medium unless bovine serum, or a fraction therefrom, was added aseptically, since the factor present in the serum is thermolabile (Dubos and Middlebrook, 1947). On the other hand, egg yolk or whole egg media may be used, but the difficulties in preparing the media render the methods uncertain and cumbersome. Hence, a thermostable...